Equest Pramox 19.5 mg/g + 121.7 mg/g Oral Gel (Moxidectin and Praziquentel Horse Wormer) - POM-VPS
Equest Pramox 19.5 mg/g + 121.7 mg/g Oral Gel controls small and large redworm, including encysted small redworm as well as other nematode species and bots and all three species of tapeworm in horses and ponies from six and a half months of age.
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Equest Pramox 19.5 mg/g + 121.7 mg/g Oral Gel
Equest Pramox 19.5 mg/g + 121.7 mg/g Oral Gel controls small and large redworm, including encysted small redworm as well as other nematode species and bots and all three species of tapeworm in horses and ponies from six and a half months of age. It is suitable for pregnant and lactating mares but must not be used in lactating mares producing milk for human consumption. The withdrawal period for meat and offal is 64 days.
Equest Pramox 19.5 mg/g + 121.7 mg/g Oral Gel has a long duration of 13 weeks, meaning that if you alternate with Equest 18.92 mg/g Oral Gel for Horses & Ponies you only need to worm 4 a year for complete bot and roundworm control.
For optimum control of bots, Equest Pramox 19.5 mg/g + 121.7 mg/g Oral Gel should be administered in the autumn, after the end of the fly season and before spring as the larvae may start to pupate and therefore are less sensitive to treatment.
Each syringe of Equest Pramox 19.5 mg/g + 121.7 mg/g Oral Gel treats 700kg and is calibrated with 25kg bodyweight graduations for accurate dosing according to body weight.
Equest Pramox 19.5 mg/g + 121.7 mg/g Oral Gel contains 2 active ingredients, Moxidectin and Praziquentel:
- Moxidectin: a second generation macrocyclic lactone of the milbemycin family. Moxidectin paralyses and kills parasites by its effect on their nervous systems.
- Praziquantel: a parasiticide widely used in many species for the specific control of tapeworm. Praziquantel is quickly absorbed via the tegument of the tapeworm and distributed evenly within the parasite. It disrupts the metabolism of the tapeworm,
resulting in contraction and paralysis of the parasite.
Equest Pramox 19.5 mg/g + 121.7 mg/g Oral Gel is indicated for treatment of mixed cestodes and nematodes or arthropods infections, caused by moxidectin and praziquantel sensitive strains of:
- Strongylus vulgaris (adult stages)
- Strongylus edentatus (adult stages)
- Triodontophorus brevicauda (adults)
- Triodontophorus serratus (adults)
- Triodontophorus tenuicollis (adults)
Small strongyles (adults and intraluminal larval stages):
- Cyathostomum spp
- Cylicocyclus spp
- Cylicostephanus spp
- Cylicodontophorus spp
- Gyalocephalus spp
- Anoplocephala perfoliata
- Anoplocephala magna
- Paranoplocephala mammillana
- Parascaris equorum (adults)
- Oxyuris equi (adult stages)
- Habronema muscae (adults)
- Gasterophilus intestinalis (L2, L3)
- Gasterophilus nasalis (L2, L3)
- Strongyloides westeri (adults)
- Trichostrongylus axei (adult stages)
- A single oral dose of 400µg moxidectin/kg bodyweight and 2.5mg praziquantel/kg bodyweight using the calibrated syringe of one gradation per 25 kg live weight.
- To ensure administration of a correct dosage, body weight should be determined as accurately as possible; accuracy of the dosing should be checked.
- Use of a scale or weight tape is recommended to ensure accurate dosing.
- Before the first dose, hold the syringe with the capped end pointing to the left and so that you can see the weight measurements and tick marks (small black lines).
- Set the syringe to zero by moving the dial ring so the left side is set at the first full black mark and depress the plunger, safely discarding any paste that is expelled.
- To dose the product, hold the syringe as previously described. Each tick mark relates to 25kg of bodyweight and to 10mg moxidectin/62.5 mg praziquantel.
- Turn the dial ring until the left side of the ring lines up with the weight of the animal.
- In the case of cestode treatment the dose of praziquantel in the product has been selected to the top end of the dosing range.
- Active Ingredients: Moxidectin 19.5mg and Praziquantel 121.7mg.
Other Ingredients: Benzyl alcohol (E1519) 220mg, Butylhydroxytoluene (E321) 0.8mg, Anhydrous colloidal silica, Ethanol, anhydrous Polysorbate 80, Ethyl cellulose, Propylene glycol dicaprylate/dicaprate.
- Do not administer to young foals less than 6.5 months old.
- Do not use in case of hypersensitivity to the active substance or to any of the excipients The product has been formulated specifically for use in horses only.
- Dogs and cats may be adversely affected by the concentration of moxidectin in this product if they are allowed to ingest spilled gel or have access to used syringes.
- In order to limit the impact of moxidectin on dung fauna, and due to insufficient data regarding environmental risk of praziquantel, horses should not be turned out onto pasture within 3 days of treatment.
- Moxidectin fulfils the criteria for a (very) persistent, bioaccumulative and toxic (PBT) substance; therefore, exposure of the environment to moxidectin must be limited to the extent possible. Treatments should be administered only when necessary and should be based on faecal egg counts or evaluation of the risk of infestation at the animal and/or herd level. In order to reduce the emission of moxidectin to surface water and based on the excretion profile of moxidectin when administered as the oral formulation to horses, treated animals should not have access to watercourses during the first week after treatment.
- Like other macrocyclic lactones, moxidectin has the potential to adversely affect non-target organisms:
- Faeces containing moxidectin excreted onto pasture by treated animals may temporarily reduce the abundance of dung feeding organisms. Following treatment of horses with the product, levels of moxidectin that are potentially toxic to dung beetles and flies may be excreted over a period of more than 1 week and may decrease dung fauna abundance.
- Moxidectin is inherently toxic to aquatic organisms including fish. The product should be used only according to the label instructions.
Special precautions for use in animals:
- To avoid overdosing, care should be taken to accurately dose foals, especially low body weight foals or pony foals.
- Do not use the same syringe to treat more than one animal unless horses are running together or in direct contact with each other in the same premises.
Special precautions to be taken by the person administering the veterinary medicinal product to animals:
- This product may cause eye irritation, skin irritation and skin sensitisation. Avoid contact with skin and eyes.
- Use protective gloves.
- Wash hands or any exposed area after use.
- Do not smoke, drink or eat while handling the product.
- In the event of eye contact flush the eye with copious amount of clean water and seek medical advice. In case of accidental ingestion, seek medical help and show the doctor the package insert.